Theses

Publications

Posters

Protein-interacting drugs: An exploration of the potential of fragment-based target prediction

Laura van Hazendonk completed Bachelor on July 5, 2016 advised by M.Sc Kiran Telukunta and evaluated by Prof. Dr. Stefan Günther

Fragmentbasierte Analyse von Struktur-Wirkungsbeziehungen kleiner Moleküle

Moritz Konrad completed Bachelor on June 15, 2016 advised by M.Sc Kiran Telukunta and evaluated by Prof. Dr. Stefan Günther

Evaluation verschiedener Prozessierungsmethoden für die Auswertung von DNA-Methylierungsdaten unterschied- licher Zelltypen mithilfe der Plattform Infinium HumanMethylation450

M.Sc Stephan Flemming completed Ph.D on April 28, 2016 advised by Prof. Dr. Stefan Günther and evaluated by Prof. Dr. Stefan Günther

Integrierte bioinformatische Methoden zur reproduzierbaren und transparenten Hochdurchsatz-Analyse von Life Science Big Data

Björn Grüning completed Ph.D on Oct. 31, 2015 advised by Prof. Dr. Stefan Günther and evaluated by Prof. Dr. Stefan Günther & Prof. M.Müller

Strukturbasierte in silico-Identifizierung vorhergesagter Polyketide produziert von modularen Typ I-Polyketidsynthasen

Dimitar Yonchev completed Dipl.-Pharm on Oct. 29, 2015 advised by Jun.-Prof. Dr. Stefan Günther and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Implementierung eines Analyseschemas für die Auswertung von DNA-Methylierungsdaten in Galaxy und Anwendung auf einen Datensatz mit rezidiven CLL-Zellen nach FCR-Therapie

Simon Bohleber completed Master of Science on Sept. 21, 2015 advised by M.Sc. Stephan Flemming and evaluated by Jun.-Prof. Dr. Stefan Günther

Identification of new inhibitors of BRWD3

Anika Nietzer completed Bachelor of Science on Aug. 27, 2015 advised by M.Sc. Mehrosh Pervaiz and evaluated by Jun.-Prof. Dr. Stefan Günther

Untersuchung der strukturellen Diversität von Naturstoffen aus Streptomyces spec

Sören Jahn completed BSc Pharm on July 31, 2015 advised by M.Sc. Xavier Lucas and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Extraction of Compound-Protein Interactions from PubMed Using the All-Paths Graph Kernel

Elham Abbasian completed Master of Science on April 20, 2015 advised by M.Sc. Kersten Döring and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Rolf Backofen

Phylogenetische Klassifizierung von Antibiotika-produzierenden Streptomyceten-Stämmen

Alina Ostendorf completed BSc Pharm on Feb. 15, 2015 advised by Dipl.-Pharm. Dennis Klementz and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Discovery of small molecules modulating protein-protein interactions

M.Sc Xavier Lucas completed Ph.D on Oct. 31, 2014 advised by Jun.-Prof. Dr. Stefan Günther and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Manfred Jung

Entwicklung einer Software zur Unterstützung der strukturbasierten Wirkstofffindung gegen Bromodomänen

Lucas Paetow completed Bachelor of Science on Sept. 29, 2014 advised by Jun.-Prof. Dr. Stefan Günther and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Oliver Einsle

Experimentelle Validierung der metabolischen Modells des Antibiotika produzierenden Streptomyces sp. Tü6071

Julian Schill completed Bachelor of Science on July 25, 2014 advised by Dipl.-Pharm. Dennis Klementz and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

ModPKSFinder - towards in silico discovery of novel polyketides

Natalia Padilla completed Master of Science on July 1, 2014 advised by Jun.-Prof. Dr. Stefan Günther and evaluated by Jun.-Prof. Dr. Stefan Günther

Pharmakophor-basierte Suche nach neuen Inhibitoren von CREBBP

Can Bittner completed Bachelor of Science on Feb. 27, 2014 advised by M.Sc. Xavier Lucas and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Manfred Jung

Automatisierte Identifizierung funktioneller Beziehungen zwischen Kleinmolekülen und Proteinen in Texten

Michael Becer completed Bachelor of Science on Jan. 27, 2014 advised by M.Sc. Kersten Döring and evaluated by Jun.-Prof. Dr. Stefan Günther & Dr. Martin Mann

Untersuchung des metabolischen Regulationsnetzwerks des Antibiotika produzirenden Streptomyces sp. Tü6071

Dennis Klementz completed Dipl.-Pharm. on Dec. 3, 2013 advised by Dr. Anika Erxleben and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Identification of Molecular Descriptors for Toxicity Prediction of Small Molecules

Lina Maren Grüger completed Bachelor of Science on Nov. 21, 2013 advised by M.Sc. Kersten Döring and evaluated by Jun.-Prof. Dr. Stefan Günther & Dr. Fabrizio Costa

Systembiologische Modellierung des Antibiotika-produzierenden Bakteriums Streptomyces sp. Tü6071

Michael Damrat completed Bachelor of Science on May 31, 2013 advised by Dr. Anika Erxleben and evaluated by Jun. - Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Analyse der Beziehung zwischen DNA Methylierung und Genexpression im humanen Genom

Wilhelm Schulz completed Bachelor of Science on April 30, 2013 advised by M.Sc. Stephan Flemming and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Manfred Jung

Charakterisierung des chemischen Raums mittels physiko-chemischer Deskriptoren

Stefan Bleher completed Bachelor of Science on Feb. 1, 2013 advised by M.Sc. Björn Grüning & M.Sc. Xavier Lucas and evaluated by Jun.-Prof. Dr. Stefan Günther & Jun.-Prof. Dr. Jennifer Andexer

Einfluss des DNA-Methylierungsmusters auf die Genregulation der menschlichen Zelle

Simon Bohleber completed Bachelor of Science on Nov. 30, 2012 advised by M.Sc. Stephan Flemming and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Manfred Jung

Etablierung der Produktion von Phenalinolactonen durch Streptomyces sp. Tü6071 im Bioreaktor

Johannes Mosch completed Diplom on Nov. 30, 2012 advised by Dr. Anika Erxleben and evaluated by Jun.-Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

Genomannotation und Charakterisierung des Avilamycin produzierenden Bakteriums Streptomyces viridochromogenes Tü57

Anna Hähnlein completed Bachelor of Science on June 28, 2012 advised by M.Sc. Björn Grüning and evaluated by Jun. - Prof. Dr. Stefan Günther & Prof. Dr. Andreas Bechthold

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